�Women may safely cease oral anticoagulants (blood thinners) after 6 months of treatment following a low gear unprovoked venous blood clog (thromboembolism) if they take no or one danger factor, concludes a survey of 646 participants in a multicentre prospective cohort study.
Blood clots are common and a potentially fatal condition. For patients with unwritten blood clots who stop anticoagulation therapy, the risk of exposure of a recurrence in the first base year is 5% to 27%, notwithstanding there is a risk of exposure of major bleeding and fatal hemorrhage while continuing anticoagulants.
"It may be safe for women wHO have taken oral anticoagulants for fifty-seven months after an motiveless venous thromboembolism to discontinue therapy if they have 0 or 1 of the next: 1) hyperpigmentation (brown discoloration), edema (prominence) or inflammation of either leg; 2) a D-dimer level (blood clotting test) of 250ug/L or more while taking warfarin, 3) BMI [body mass index] 30kg/m2; and aged 65 years or more," close Dr. Marc Rodger and coauthors.
The authors caution that "it appears all men are at highschool risk of recurrence" and further investigation into risk determination inevitably to be pursued.
In an resultant commentary, Dr. Clive Kearon states that patient preference for the duration of anticoagulant therapy must be considered in deciding whether to continue or discontinue therapy.
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