�Women may safely cease oral anticoagulants (blood thinners) after 6 months of treatment following a low gear unprovoked venous blood clog (thromboembolism) if they take no or one danger factor, concludes a survey of 646 participants in a multicentre prospective cohort study.
Blood clots are common and a potentially fatal condition. For patients with unwritten blood clots who stop anticoagulation therapy, the risk of exposure of a recurrence in the first base year is 5% to 27%, notwithstanding there is a risk of exposure of major bleeding and fatal hemorrhage while continuing anticoagulants.
"It may be safe for women wHO have taken oral anticoagulants for fifty-seven months after an motiveless venous thromboembolism to discontinue therapy if they have 0 or 1 of the next: 1) hyperpigmentation (brown discoloration), edema (prominence) or inflammation of either leg; 2) a D-dimer level (blood clotting test) of 250ug/L or more while taking warfarin, 3) BMI [body mass index] 30kg/m2; and aged 65 years or more," close Dr. Marc Rodger and coauthors.
The authors caution that "it appears all men are at highschool risk of recurrence" and further investigation into risk determination inevitably to be pursued.
In an resultant commentary, Dr. Clive Kearon states that patient preference for the duration of anticoagulant therapy must be considered in deciding whether to continue or discontinue therapy.
About CMAJ (Canadian Medical Association Journal)
CMAJ is the leading health sciences journal in Canada. CMAJ is a universal medical diary publishing original research and review articles, commentaries and editorials, practice updates, an arts and ideas section and health news. Published continuously since 1911, new issues are uploaded on http://www.cmaj.ca every arcsecond Monday at 4:30 p.m. EST/EDT. hypertext transfer protocol://www.cmaj.ca contains the finish editorial table of contents of CMAJ, supplemented by a variety of interactive features and additional content.
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Saturday, 30 August 2008
Sunday, 10 August 2008
Searing Meadow
Artist: Searing Meadow
Genre(s):
Metal: Death,Black
Discography:
Once Adored
Year: 2001
Tracks: 3
Mariah Carey spends 2.5 million on mansion
Tuesday, 1 July 2008
Potential Bad Boy
Artist: Potential Bad Boy
Genre(s):
Drum & Bass
Discography:
JHR001 DD
Year: 2005
Tracks: 2
Play It Kik It Ep RPG005 Viny
Year: 2004
Tracks: 4
Thursday, 19 June 2008
Encounter with Luna, the killer whale, is lesson in stewardship
In September 2005, I accompanied two Mowachaht/Muchalaht fisheries experts up the northwest coast of Vancouver Island aboard the tribe's lightweight Zodiac. As we returned to the deep canyon fjord of Nootka Sound, a call came over the radio from the First Nation's stewardship boat. Luna was playing at the Gold River dock.
Within minutes, we were looking for the mischievous orca. At first there was no sign of him. We idled slowly from one end of the dock to the other. "False alarm," I thought. Then I saw his head bob up beside the rusty hull of a large boat.
Fisheries coordinator Jamie James leaned over the side of the Zodiac and snapped his fingers below the surface of the water. Luna immediately swam over to us like a happy sea puppy. He seemed to recognize Jamie, and he eyed me with curiosity. I was stunned.
For the next hour, a rambunctious Luna swam back and forth between our boats as we led him from potential trouble and out toward the ocean. He gently pushed us from side to side.
He dove with playful agility beneath the hull and pushed us along from the back of the Zodiac. Luna did backflips and splashed the water with his tail and pectoral fins. He surfed in our wake and rubbed up against the side of the boat.
All I could say — over and over — was, "He's amazing!" I feel blessed to have encountered this special creature. He struck me as a sweet, gentle, childlike spirit.
I took many photographs of Luna that day and have since written about the iconic orca for several publications. It is a compelling narrative.
At a time when salmon runs are at historic lows, northern glaciers are melting at an alarming rate and earthquakes and cyclones are wiping out entire communities, Luna's presence among humans serves as a poignant reminder about our responsibility as stewards over this fragile Earth and its endangered creatures.
Stephan Michaels
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Thursday, 12 June 2008
Next Generation Iphone Launched
The next generation of mobile from Apple - the iPhone 3G - has been revealed to expectant audiences at the World Wide Developers' Conference in San Francisco.
Initial reaction to the product was warm, but many of the technical innovations had been widely expected.
The device's 3G capability had been rumoured, along with a new Global Position System (GPS), allowing users to track their movements.
For buyers it was the price that is likely to prove most attractive.
While the first generation of iPhones were priced at $599 (£300), falling to $399 (£200), the basic (eight gigabyte) version of the new model will go on sale for just $199 (£100).
A 16 gig model will be available to American consumers when the new device goes on sale on July 11th, priced $299 (£150).
Apple chief executive Steve Jobs admitted price was the number one reason the previous incarnation of the product had perhaps failed to meet expectations.
With this in mind, Apple has significantly lowered the price in an attempt to expand market share.
However, the phone will remain exclusive to the 02 network when it is released in the UK – causing some buyers to complain of the negative price connotations of the monopoly.
Apple also announced improvements in download speeds and other technical abilities.
Mr Jobs confirmed there are to be 300 hours of standby time, five hours of 3G talk time, five to six hours of browsing, seven hours of video and 24 hours of audio power.
The new device is expected to be launched in Europe in November.
10/06/2008 11:39:28
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Friday, 6 June 2008
Harrison Ford - Indiana Jones Makes 45m In Midnight Screenings
The new Indiana Jones film, the Kingdom of the Crystal Skull, has reportedly made $4.5 million (£2.27 million) at the US box office after midnight screenings on Wednesday night.
Variety magazine claimed that the fourth Indiana Jones film also made $2.2 million (£1.1 million) in France, Belgium and Switzerland.
Reviews of the eagerly awaited film have been mixed with some critics hailing the return of the famous archaeologist, 19 years after he last appeared on the big screen, as a triumph. Others have been less that flattering regarding Harrison Ford's age and the film's script.
The film received its international premier earlier this week at the Cannes festival.
At the famous film event Ford dismissed criticism of the film claiming that he made the picture for the paying public not the critics.
Indiana Jones, created by George Lucas and Steven Spielberg, first appeared on cinema screens in 1981 in the film Raiders of the Lost Ark.
The franchise included two other movies including Temple of Doom in 1984 and the Last Crusade in 1989.
23/05/2008 12:15:17
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Thursday, 29 May 2008
Gallagher & Appleton tie the knot
Oasis frontman Liam Gallagher has married his long-term partner, singer Nicole Appleton.
According to reports, the couple tied the knot in a low-key civil ceremony in London on Valentine's Day.
The wedding reception reportedly took place at the five-star Landmark Hotel in London.
Appleton has previously spoken about marrying Gallagher, saying: "Marriage is important to me and I love the idea of being married."
The couple, who have been together for nearly eight years, have a seven-year-old son together.
According to reports, the couple tied the knot in a low-key civil ceremony in London on Valentine's Day.
The wedding reception reportedly took place at the five-star Landmark Hotel in London.
Appleton has previously spoken about marrying Gallagher, saying: "Marriage is important to me and I love the idea of being married."
The couple, who have been together for nearly eight years, have a seven-year-old son together.
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